Reglan iv vs oral gavage) at 30 days after the beginning of treatment at dosage 150 or mg. The effect of gavage on response was quantitated by means of a logarithmic transformation, in accordance with Fisher exact test. F ig. 3 View largeDownload slide Effect of gavage in rats oral at 150 mg/kg BW (iv) or (vl) for 24 weeks. The treatment was started when there were signs of the first tumour in oral mucosa. Statistical analysis Statistical significance of the effect gavage on tumour growth could be established only if data from multiple groups were treated individually or if a significance value was not possible with the use of Bonferroni method. When two groups were given the same gavage, they were pooled by means of a random sample to determine the effect of gavage. data from the pooled studies were examined statistically. Results obtained from the study group that received a single dose of the chemical substance are presented as the mean ± Maxalt 10 mg online s.e.m. statistical significance of the effect as a result of single dose gavage cannot be established. The analyses were done by using the software package, Statistica for Windows (version 9.2; StatSoft, Tulsa, USA). F ig. 4 View largeDownload slide Influence of gavage therapy as a function of the duration treatment. Mean±s.e.m., and significance value of each variable at 30 days by means of Mann-Whitney U test after normalization for the number of tumour patients treated. Table 2 Chemical treatment Placebo Chemotherapy 150 mg iv 30 days n = 17 16 15 14 Number of tumour patients 17 19 22 Number of tumour patients/group (number tumours/group) 6.1 5.3 9.2 4.6 6.2 7.7 Number of patients, at onset tumour 15 11 13 Number of patients, at onset tumour by day 60 6.5 4 5 6 Number of patients, at onset tumour by day 180 18 12 7 11 Number of patients, at onset tumour by day 270 34 17 18 29 Number of patients, at start treatment 30 14 8 12 20 10 15 Duration of Ator 40 Pills $203 - $185 Per pill treatment (days) 20.1 ± 2.9 16.3 3.8 16.1 3.4 20.1 ± 3.3 16.7 3.8 16.4 3.1 18.8 ± 2.3 19.5 2.9 18.0 20.0 ± 3.2 p value (treatment effect/number of tumours studied) 0.1614 (0.1416–0.1803, p = 0.0614) 0.1547 (0.1121–0.1272, 0.0278) 0.0788 (0.1412–0.1489, p = 0.5143) 0.1667 (0.1279–0.1716, 0.0618) 0.1664 (0.1128–0.1420, p = 0.0286) 0.1473 buy atorvastatin 40 mg (0.1526–0.1659, 0.0577) p value (treatment effect/tumour size) 0.0002 (0.0000–0.0010) 0.0001 (0.0000–0.0003) 0.0006 (0.0008–0.0002) 0.0005 (0.0003–0.0009, p = 0.9997) 0.0001 (0.0001–0.0010) value (treatment effect/tumour stage) 0.0245 (0.0140–0.0275) <0.001 (0.0002–0.0085) (0.0003–0.0070) 0.0322 (0.0331–0.0350) 0.1276 atorvastatin 40 mg coupon (0.0934–0.1333) 0.2170 (0.1616–0)

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